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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TSHR HGNC:12373 (HGNC)
7253 (Entrez Gene)
603372 (OMIM)
HGNC homology
Chr14 q31 Chr14:80954989-81146302 (+)
Hyperthyroidism, Familial Gestational
Hyperthyroidism, Nonautoimmune
Hypothyroidism, Congenital, Nongoitrous, 1; CHNG1
Thyroid-Stimulating Hormone Receptor; TSHR
P16473 (UniProt | EBI)
NM_000369 (RefSeq)
mouse Tshr MGI:98849 (MGI)
22095 (Entrez Gene)
Gene Tree
Chr12 44.51 cM Chr12:91400994-91540509 (+)
Hypothyroidism, Congenital, Nongoitrous, 1; CHNG1
OTTMUSG00000049745 (VEGA)
OTTMUSP00000068492 (VEGA)
OTTMUST00000126709 (VEGA)
rat Tshr 25360 (Entrez Gene)
Chr6 q31 P21463 (UniProt | EBI)
NM_012888 (RefSeq)
chimpanzee TSHR 453077 (Entrez Gene)
Chr14 XP_009426513 (RefSeq)
rhesus macaque TSHR 574251 (Entrez Gene)
Chr7 NP_001182324 (RefSeq)
NM_001195395 (RefSeq)
cattle TSHR 281553 (Entrez Gene)
Chr10 Q27987 (UniProt | EBI)
NM_174206 (RefSeq)
dog TSHR 403968 (Entrez Gene)
Chr8 P14763 (UniProt | EBI)
NM_001003285 (RefSeq)
chicken TSHR 428900 (Entrez Gene)
Chr5 NP_001180518 (RefSeq)
NM_001033850 (RefSeq)
western clawed frog tshr 100492843 (Entrez Gene)
ChrUN XP_002938419 (RefSeq)
zebrafish tshr 560609 (Entrez Gene)
Chr20 NP_001139235 (RefSeq)
NM_001145763 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory