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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FKTN HGNC:3622 (HGNC)
2218 (Entrez Gene)
607440 (OMIM)
HGNC homology
Chr9 q31.2 Chr9:105558119-105641118 (+)
Cardiomyopathy, Dilated, 1x; CMD1X
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 1; MDDGA1
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 4; MDDGA4
Muscular Dystrophy-Dystroglycanopathy (congenital without Mental Retardation), Type B, 4; MDDGB4
Muscular Dystrophy-Dystroglycanopathy (limb-Girdle), Type C, 4; MDDGC4
O75072 (UniProt | EBI)
NM_001198963 (RefSeq)
mouse Fktn MGI:2179507 (MGI)
246179 (Entrez Gene)
Gene Tree
Chr4 28.74 cM Chr4:53713998-53765785 (+)
Muscular Dystrophy-Dystroglycanopathy (congenital with Brain and Eye Anomalies), Type A, 4; MDDGA4
OTTMUSG00000007009 (VEGA)
OTTMUSP00000007427 (VEGA)
OTTMUST00000016204 (VEGA)
rat Fktn 362520 (Entrez Gene)
Chr5 q24 NP_001102137 (RefSeq)
NM_001108667 (RefSeq)
chimpanzee FKTN 464634 (Entrez Gene)
Chr9 XP_009455336 (RefSeq)
rhesus macaque FKTN 712201 (Entrez Gene)
Chr15 NP_001244424 (RefSeq)
NM_001257495 (RefSeq)
cattle FKTN 536891 (Entrez Gene)
Chr8 XP_015320142 (RefSeq)
dog FKTN 481652 (Entrez Gene)
Chr11 XP_005626955 (RefSeq)
chicken FKTN 427303 (Entrez Gene)
ChrZ XP_004949412 (RefSeq)
western clawed frog fktn 100124956 (Entrez Gene)
ChrUN NP_001096364 (RefSeq)
NM_001102894 (RefSeq)
zebrafish fktn 100006345 (Entrez Gene)
Chr5 NP_001036159 (RefSeq)
NM_001042694 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory