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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
314

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TSC1 HGNC:12362 (HGNC)
7248 (Entrez Gene)
605284 (OMIM)
Chr9 q34 Chr9:132891348-132944707 (-)
GRCh38
Focal Cortical Dysplasia of Taylor; FCDT
Lymphangioleiomyomatosis; LAM
Tuberous Sclerosis 1; TSC1
Q92574 (UniProt | EBI)
NM_000368 (RefSeq)
mouse Tsc1 MGI:1929183 (MGI)
64930 (Entrez Gene)
Gene Tree
VISTA-Point
Chr2 19.38 cM Chr2:28641228-28691167 (+)
GRCm38
Polycystic Kidney Disease, Autosomal Recessive; ARPKD
Tuberous Sclerosis 1; TSC1
OTTMUSG00000011747 (VEGA)
OTTMUSP00000012518 (VEGA)
OTTMUST00000027552 (VEGA)
rat Tsc1 60445 (Entrez Gene)
Chr3 p12 Q9Z136 (UniProt | EBI)
NM_021854 (RefSeq)
chimpanzee TSC1 464818 (Entrez Gene)
Chr9 XP_001168941 (RefSeq)
rhesus macaque TSC1 714645 (Entrez Gene)
Chr15 XP_001103846 (RefSeq)
cattle TSC1 533440 (Entrez Gene)
Chr11 XP_003582888 (RefSeq)
NM_001075992 (RefSeq)
dog TSC1 480688 (Entrez Gene)
Chr9 XP_537808 (RefSeq)
chicken TSC1 417166 (Entrez Gene)
Chr17 XP_415449 (RefSeq)
western clawed frog tsc1 100380126 (Entrez Gene)
ChrUN XP_002944681 (RefSeq)
zebrafish tsc1a 337167 (Entrez Gene)
Chr5 NP_956346 (RefSeq)
NM_200052 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory