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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
31310

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SMAD4 HGNC:6770 (HGNC)
4089 (Entrez Gene)
600993 (OMIM)
Chr18 q21.1 Chr18:51030213-51085042 (+)
GRCh38
Juvenile Polyposis Syndrome; JPS
Juvenile Polyposis/Hereditary Hemorrhagic Telangiectasia Syndrome;
Myhre Syndrome; MYHRS
Pancreatic Cancer
Q13485 (UniProt | EBI)
NM_005359 (RefSeq)
mouse Smad4 MGI:894293 (MGI)
17128 (Entrez Gene)
Gene Tree
VISTA-Point
Chr18 49.51 cM Chr18:73639009-73703780 (-)
GRCm38
Juvenile Polyposis Syndrome; JPS
OTTMUSG00000021090 (VEGA)
OTTMUSP00000023201 (VEGA)
OTTMUST00000049897 (VEGA)
rat Smad4 50554 (Entrez Gene)
Chr18 q12.3 O70437 (UniProt | EBI)
NM_019275 (RefSeq)
chimpanzee SMAD4 468537 (Entrez Gene)
Chr18 XP_001155601 (RefSeq)
rhesus macaque SMAD4 701803 (Entrez Gene)
Chr18 NP_001248019 (RefSeq)
NM_001261090 (RefSeq)
cattle SMAD4 540248 (Entrez Gene)
Chr24 Q1HE26 (UniProt | EBI)
NM_001076209 (RefSeq)
dog SMAD4 476196 (Entrez Gene)
Chr1 XP_849370 (RefSeq)
zebrafish zmp:0000000768 559111 (Entrez Gene)
Chr10 NP_001116172 (RefSeq)
NM_001122700 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory