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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
313

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TPMT HGNC:12014 (HGNC)
7172 (Entrez Gene)
Chr6 p22.3 Chr6:18128311-18155143 (-)
GRCh38
Thiopurine S-Methyltransferase Deficiency
P51580 (UniProt | EBI)
NM_000367 (RefSeq)
mouse Tpmt MGI:98812 (MGI)
22017 (Entrez Gene)
Gene Tree
VISTA-Point
Chr13 24.5 cM Chr13:47025170-47044737 (-)
GRCm38
Thiopurine S-Methyltransferase Deficiency
OTTMUSG00000024764 (VEGA)
OTTMUSP00000029822 (VEGA)
OTTMUST00000060976 (VEGA)
rat Tpmt 690050 (Entrez Gene)
Chr17 p13 Q9Z0T0 (UniProt | EBI)
NM_001079531 (RefSeq)
chimpanzee TPMT 471863 (Entrez Gene)
Chr6 Q3BCR8 (UniProt | EBI)
NM_001035519 (RefSeq)
rhesus macaque TPMT 704564 (Entrez Gene)
Chr4 XP_001097433 (RefSeq)
cattle TPMT 511644 (Entrez Gene)
Chr23 Q17QQ2 (UniProt | EBI)
NM_001075531 (RefSeq)
dog TPMT 403536 (Entrez Gene)
Chr35 Q8HX86 (UniProt | EBI)
NM_001003015 (RefSeq)
chicken TPMT 420830 (Entrez Gene)
Chr2 XP_418921 (RefSeq)
western clawed frog tpmt 549164 (Entrez Gene)
ChrUN NP_001016410 (RefSeq)
NM_001016410 (RefSeq)
zebrafish tpmt.1 436842 (Entrez Gene)
Chr19 Q504A5 (UniProt | EBI)
NM_001002569 (RefSeq)
tpmt.2 573111 (Entrez Gene)
Chr19 NP_001028758 (RefSeq)
NM_001033586 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory