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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ORC1 HGNC:8487 (HGNC)
4998 (Entrez Gene)
601902 (OMIM)
HGNC homology
Chr1 p32 Chr1:52372829-52404471 (-)
Meier-Gorlin Syndrome 1; MGORS1
Q13415 (UniProt | EBI)
NM_004153 (RefSeq)
mouse Orc1 MGI:1328337 (MGI)
18392 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 50.64 cM Chr4:108579423-108614833 (+)
OTTMUSG00000008240 (VEGA)
OTTMUSP00000008599 (VEGA)
OTTMUST00000018729 (VEGA)
rat Orc1 313479 (Entrez Gene)
Chr5 q35 Q80Z32 (UniProt | EBI)
NM_177931 (RefSeq)
chimpanzee ORC1 456857 (Entrez Gene)
Chr1 XP_009456090 (RefSeq)
rhesus macaque ORC1 713271 (Entrez Gene)
Chr1 XP_002801618 (RefSeq)
cattle ORC1 513523 (Entrez Gene)
Chr3 Q58DC8 (UniProt | EBI)
NM_001014918 (RefSeq)
dog ORC1 100855917 (Entrez Gene)
Chr15 XP_005629059 (RefSeq)
chicken ORC1 424640 (Entrez Gene)
Chr8 NP_001026457 (RefSeq)
NM_001031286 (RefSeq)
western clawed frog orc1 734048 (Entrez Gene)
ChrUN NP_001039194 (RefSeq)
NM_001045729 (RefSeq)
zebrafish orc1 554509 (Entrez Gene)
Chr6 NP_956227 (RefSeq)
NM_199933 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory