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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SQSTM1 HGNC:11280 (HGNC)
8878 (Entrez Gene)
601530 (OMIM)
Sequestosome 1 (MyGene.info)
HGNC homology
Chr5 q35.3 Chr5:179806388-179838078 (+)
Paget's disease of bone
Q13501 (UniProt | EBI)
NM_001142299 (RefSeq)
mouse Sqstm1 MGI:107931 (MGI)
18412 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 30.36 cM Chr11:50199366-50210827 (-)
Paget's disease of bone
OTTMUSG00000005574 (VEGA)
OTTMUSP00000005736 (VEGA)
OTTMUST00000012391 (VEGA)
rat Sqstm1 113894 (Entrez Gene)
Chr10 q22 O08623 (UniProt | EBI)
NM_175843 (RefSeq)
chimpanzee SQSTM1 462333 (Entrez Gene)
Chr5 XP_016809937 (RefSeq)
cattle SQSTM1 338045 (Entrez Gene)
Chr7 NP_788814 (RefSeq)
NM_176641 (RefSeq)
chicken SQSTM1 770805 (Entrez Gene)
Chr13 XP_004945010 (RefSeq)
zebrafish sqstm1 406452 (Entrez Gene)
Chr14 NP_001299842 (RefSeq)
NM_213173 (RefSeq)
frog, western clawed sqstm1 493277 (Entrez Gene)
Chr3 NP_001007894 (RefSeq)
NM_001007893 (RefSeq)
macaque, rhesus SQSTM1 705481 (Entrez Gene)
Chr6 NP_001253287 (RefSeq)
NM_001266358 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory