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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPG7 HGNC:11237 (HGNC)
6687 (Entrez Gene)
602783 (OMIM)
HGNC homology
Chr16 q24.3 Chr16:89508381-89557768 (+)
Spastic Paraplegia 7, Autosomal Recessive; SPG7
Q9UQ90 (UniProt | EBI)
NM_003119 (RefSeq)
mouse Spg7 MGI:2385906 (MGI)
234847 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 72.04 cM Chr8:123062942-123097760 (+)
Spastic Paraplegia 7, Autosomal Recessive; SPG7
OTTMUSG00000022131 (VEGA)
OTTMUSP00000024918 (VEGA)
OTTMUST00000052521 (VEGA)
rat Spg7 353231 (Entrez Gene)
Chr19 q12 Q7TT47 (UniProt | EBI)
NM_181388 (RefSeq)
chimpanzee SPG7 737127 (Entrez Gene)
Chr16 XP_009429720 (RefSeq)
rhesus macaque SPG7 699488 (Entrez Gene)
Chr20 XP_014982305 (RefSeq)
cattle SPG7 515269 (Entrez Gene)
Chr18 NP_001095492 (RefSeq)
NM_001102022 (RefSeq)
dog SPG7 489657 (Entrez Gene)
Chr5 XP_546777 (RefSeq)
chicken SPG7 415843 (Entrez Gene)
Chr11 NP_001012545 (RefSeq)
NM_001012527 (RefSeq)
western clawed frog spg7 100485977 (Entrez Gene)
ChrUN XP_002933705 (RefSeq)
zebrafish spg7 794740 (Entrez Gene)
Chr7 XP_001923118 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory