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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HTRA1 HGNC:9476 (HGNC)
5654 (Entrez Gene)
602194 (OMIM)
HGNC homology
Chr10 q26.3 Chr10:122461525-122514908 (+)
Cerebral Arteriopathy, Autosomal Recessive, with Subcortical Infarcts and Leukoencephalopathy; CARASIL
Macular Degeneration, Age-Related, 7; ARMD7
Q92743 (UniProt | EBI)
NM_002775 (RefSeq)
mouse Htra1 MGI:1929076 (MGI)
56213 (Entrez Gene)
Gene Tree
Chr7 73.2 cM Chr7:130936111-130985660 (+)
OTTMUSG00000031663 (VEGA)
OTTMUSP00000041705 (VEGA)
OTTMUST00000078440 (VEGA)
rat Htra1 65164 (Entrez Gene)
Chr1 q37 Q9QZK5 (UniProt | EBI)
NM_031721 (RefSeq)
rhesus macaque HTRA1 705855 (Entrez Gene)
Chr9 NP_001245105 (RefSeq)
NM_001258176 (RefSeq)
cattle HTRA1 282326 (Entrez Gene)
Chr26 F1N152 (UniProt | EBI)
NM_001282082 (RefSeq)
western clawed frog htra1 780187 (Entrez Gene)
ChrUN A4IHA1 (UniProt | EBI)
NM_001079262 (RefSeq)
zebrafish htra1a 431766 (Entrez Gene)
Chr17 Q6GMI0 (UniProt | EBI)
NM_001002219 (RefSeq)
htra1b 565082 (Entrez Gene)
Chr12 A9JRB3 (UniProt | EBI)
NM_001111182 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory