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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FOXO3 HGNC:3821 (HGNC)
2309 (Entrez Gene)
602681 (OMIM)
FOXO3 (MyGene.info)
HGNC homology
Chr6 q21 Chr6:108559823-108684769 (+)
O43524 (UniProt | EBI)
NM_001455 (RefSeq)
mouse Foxo3 MGI:1890081 (MGI)
56484 (Entrez Gene)
Gene Tree
HGNC homology
Chr10 22.79 cM Chr10:42181841-42276755 (-)
dermoid cyst of ovary
ENSMUSG00000048756 (Ensembl Gene Model)
ENSMUSP00000135380 (Ensembl)
ENSMUST00000175881 (Ensembl)
rat Foxo3 294515 (Entrez Gene)
Chr20 q12-q13 NP_001099865 (RefSeq)
NM_001106395 (RefSeq)
chimpanzee FOXO3 462921 (Entrez Gene)
Chr6 XP_016811571 (RefSeq)
cattle FOXO3 535530 (Entrez Gene)
Chr9 NP_001193012 (RefSeq)
NM_001206083 (RefSeq)
dog FOXO3 481954 (Entrez Gene)
Chr12 XP_003639448 (RefSeq)
chicken FOXO3 421769 (Entrez Gene)
Chr3 XP_001234496 (RefSeq)
zebrafish foxo3b 30296 (Entrez Gene)
Chr20 NP_571160 (RefSeq)
NM_131085 (RefSeq)
frog, western clawed foxo3 100125025 (Entrez Gene)
Chr5 NP_001096419 (RefSeq)
NM_001102949 (RefSeq)
macaque, rhesus FOXO3 700731 (Entrez Gene)
Chr4 XP_001093593 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory