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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PTGS2 HGNC:9605 (HGNC)
5743 (Entrez Gene)
600262 (OMIM)
HGNC homology
Chr1 q31.1 Chr1:186671812-186680427 (-)
P35354 (UniProt | EBI)
NM_000963 (RefSeq)
mouse Ptgs2 MGI:97798 (MGI)
19225 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 63.84 cM Chr1:150100031-150108227 (+)
ENSMUSG00000032487 (Ensembl Gene Model)
ENSMUSP00000035065 (Ensembl)
ENSMUST00000035065 (Ensembl)
rat Ptgs2 29527 (Entrez Gene)
Chr13 q21 P35355 (UniProt | EBI)
NM_017232 (RefSeq)
chimpanzee PTGS2 469616 (Entrez Gene)
Chr1 XP_524999 (RefSeq)
cattle PTGS2 282023 (Entrez Gene)
Chr16 O62698 (UniProt | EBI)
NM_174445 (RefSeq)
dog PTGS2 442942 (Entrez Gene)
Chr7 NP_001003354 (RefSeq)
NM_001003354 (RefSeq)
chicken PTGS2 396451 (Entrez Gene)
Chr8 P27607 (UniProt | EBI)
NM_001167719 (RefSeq)
zebrafish ptgs2b 559020 (Entrez Gene)
Chr20 NP_001020675 (RefSeq)
NM_001025504 (RefSeq)
frog, western clawed ptgs2 595089 (Entrez Gene)
Chr4 NP_001025697 (RefSeq)
NM_001030526 (RefSeq)
macaque, rhesus PTGS2 716671 (Entrez Gene)
Chr1 XP_001107538 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory