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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AIFM1 HGNC:8768 (HGNC)
9131 (Entrez Gene)
AIFM1 (MyGene.info)
HGNC homology
ChrX q26.1 ChrX:130129362-130165887 (-)
Charcot-Marie-Tooth disease X-linked recessive 4
combined oxidative phosphorylation deficiency 6
O95831 (UniProt | EBI)
NM_001130846 (RefSeq)
mouse Aifm1 MGI:1349419 (MGI)
26926 (Entrez Gene)
Gene Tree
HGNC homology
ChrX 25.68 cM ChrX:48474944-48513563 (-)
mitochondrial complex I deficiency
26926 (NCBI Gene Model)
Q9Z0X1 (UniProt | EBI)
NM_012019 (RefSeq)
rat Aifm1 83533 (Entrez Gene)
ChrX q36 Q9JM53 (UniProt | EBI)
NM_031356 (RefSeq)
chimpanzee AIFM1 100615914 (Entrez Gene)
ChrX XP_016799367 (RefSeq)
cattle AIFM1 535714 (Entrez Gene)
ChrX NP_001179913 (RefSeq)
NM_001192984 (RefSeq)
dog AIFM1 481048 (Entrez Gene)
ChrX XP_538170 (RefSeq)
chicken AIFM1 428688 (Entrez Gene)
Chr4 NP_001007491 (RefSeq)
NM_001007490 (RefSeq)
zebrafish aifm1 373125 (Entrez Gene)
Chr5 NP_956396 (RefSeq)
NM_200102 (RefSeq)
frog, western clawed aifm1 549998 (Entrez Gene)
Chr8 NP_001017244 (RefSeq)
NM_001017244 (RefSeq)
macaque, rhesus AIFM1 702773 (Entrez Gene)
ChrX NP_001244807 (RefSeq)
NM_001257878 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory