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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
30994

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HMGCR HGNC:5006 (HGNC)
3156 (Entrez Gene)
142910 (OMIM)
Chr5 q13.3-q14 Chr5:75337168-75362101 (+)
GRCh38
3-hydroxy-3-Methylglutaryl-Coa Reductase; HMGCR
P04035 (UniProt | EBI)
NM_000859 (RefSeq)
mouse Hmgcr MGI:96159 (MGI)
15357 (Entrez Gene)
Gene Tree
VISTA-Point
Chr13 50.65 cM Chr13:96648967-96670936 (-)
GRCm38
OTTMUSG00000035511 (VEGA)
OTTMUSP00000050014 (VEGA)
OTTMUST00000090933 (VEGA)
rat Hmgcr 25675 (Entrez Gene)
Chr2 q12 P51639 (UniProt | EBI)
NM_013134 (RefSeq)
chimpanzee HMGCR 471516 (Entrez Gene)
Chr5 XP_001148405 (RefSeq)
rhesus macaque HMGCR 705479 (Entrez Gene)
Chr6 XP_001104536 (RefSeq)
dog HMGCR 479182 (Entrez Gene)
Chr3 XP_536323 (RefSeq)
chicken HMGCR 395145 (Entrez Gene)
ChrZ NP_989816 (RefSeq)
NM_204485 (RefSeq)
western clawed frog hmgcr 100380121 (Entrez Gene)
ChrUN XP_002934890 (RefSeq)
zebrafish hmgcra 559054 (Entrez Gene)
Chr5 NP_001073446 (RefSeq)
NM_001079977 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory