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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human HMGCR HGNC:5006 (HGNC)
3156 (Entrez Gene)
142910 (OMIM)
HMG-CoA reductase (MyGene.info)
HGNC homology
Chr5 q13.3 Chr5:75336334-75362101 (+)
P04035 (UniProt | EBI)
NM_001130996 (RefSeq)
mouse Hmgcr MGI:96159 (MGI)
15357 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 50.65 cM Chr13:96648967-96670936 (-)
ENSMUSG00000021670 (Ensembl Gene Model)
ENSMUSP00000022176 (Ensembl)
ENSMUST00000022176 (Ensembl)
rat Hmgcr 25675 (Entrez Gene)
Chr2 q12 P51639 (UniProt | EBI)
NM_013134 (RefSeq)
chimpanzee HMGCR 471516 (Entrez Gene)
Chr5 XP_016808621 (RefSeq)
cattle HMGCR 407159 (Entrez Gene)
Chr10 A7Z064 (UniProt | EBI)
NM_001105613 (RefSeq)
dog HMGCR 479182 (Entrez Gene)
Chr3 XP_536323 (RefSeq)
chicken HMGCR 395145 (Entrez Gene)
ChrZ NP_989816 (RefSeq)
NM_204485 (RefSeq)
zebrafish hmgcra 559054 (Entrez Gene)
Chr5 NP_001073446 (RefSeq)
NM_001079977 (RefSeq)
frog, western clawed hmgcr 100380121 (Entrez Gene)
Chr1 XP_004910453 (RefSeq)
macaque, rhesus HMGCR 705479 (Entrez Gene)
Chr6 XP_002804463 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory