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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TYR HGNC:12442 (HGNC)
7299 (Entrez Gene)
606933 (OMIM)
Tyrosinase (MyGene.info)
HGNC homology
Chr11 q14.3 Chr11:89177565-89295759 (+)
ocular albinism with sensorineural deafness
P14679 (UniProt | EBI)
NM_000372 (RefSeq)
mouse Tyr MGI:98880 (MGI)
22173 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 49.01 cM Chr7:87424771-87493512 (-)
autistic disorder
Hirschsprung's disease
oculocutaneous albinism
OTTMUSG00000059417 (VEGA)
OTTMUSP00000075988 (VEGA)
OTTMUST00000145848 (VEGA)
rat Tyr 308800 (Entrez Gene)
Chr1 q32 NP_001101005 (RefSeq)
NM_001107535 (RefSeq)
chimpanzee TYR 451473 (Entrez Gene)
Chr11 XP_001136041 (RefSeq)
cattle TYR 280951 (Entrez Gene)
Chr29 qter Q8MIU0 (UniProt | EBI)
NM_181001 (RefSeq)
dog TYR 403405 (Entrez Gene)
Chr21 P54834 (UniProt | EBI)
NM_001002941 (RefSeq)
chicken TYR 373971 (Entrez Gene)
Chr1 P55024 (UniProt | EBI)
NM_204160 (RefSeq)
zebrafish tyr 30207 (Entrez Gene)
Chr15 NP_571088 (RefSeq)
NM_131013 (RefSeq)
frog, western clawed tyr 100125152 (Entrez Gene)
Chr2 NP_001096518 (RefSeq)
NM_001103048 (RefSeq)
macaque, rhesus TYR 705792 (Entrez Gene)
Chr14 XP_001105033 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory