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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
30969

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TYR HGNC:12442 (HGNC)
7299 (Entrez Gene)
Chr11 q14.3 Chr11:89177872-89295759 (+)
GRCh38
Albinism, Ocular, with Sensorineural Deafness
Albinism, Oculocutaneous, Type IA; OCA1A
Albinism, Oculocutaneous, Type IB; OCA1B
P14679 (UniProt | EBI)
NM_000372 (RefSeq)
mouse Tyr MGI:98880 (MGI)
22173 (Entrez Gene)
Gene Tree
VISTA-Point
Chr7 49.01 cM Chr7:87427405-87493411 (-)
GRCm38
Albinism, Oculocutaneous, Type IA; OCA1A
Albinism, Oculocutaneous, Type IB; OCA1B
Glaucoma 3, Primary Congenital, A; GLC3A
22173 (NCBI Gene Model)
P11344 (UniProt | EBI)
NM_011661 (RefSeq)
rat Tyr 308800 (Entrez Gene)
Chr1 q32 NP_001101005 (RefSeq)
NM_001107535 (RefSeq)
chimpanzee TYR 451473 (Entrez Gene)
Chr11 XP_001136041 (RefSeq)
rhesus macaque TYR 705792 (Entrez Gene)
Chr14 XP_001105033 (RefSeq)
dog TYR 403405 (Entrez Gene)
Chr21 P54834 (UniProt | EBI)
NM_001002941 (RefSeq)
chicken TYR 373971 (Entrez Gene)
Chr1 P55024 (UniProt | EBI)
NM_204160 (RefSeq)
zebrafish tyr 30207 (Entrez Gene)
Chr15 NP_571088 (RefSeq)
NM_131013 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory