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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FBN1 HGNC:3603 (HGNC)
2200 (Entrez Gene)
134797 (OMIM)
FBN1 (MyGene.info)
HGNC homology
Chr15 q21.1 Chr15:48408306-48645788 (-)
acromicric dysplasia
autosomal dominant isolated ectopia lentis 1
geleophysic dysplasia 2
Marfan syndrome
stiff skin syndrome
Weill-Marchesani syndrome
P35555 (UniProt | EBI)
NM_000138 (RefSeq)
mouse Fbn1 MGI:95489 (MGI)
14118 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 61.38 cM Chr2:125300594-125506485 (-)
heart disease
Marfan syndrome
pulmonary emphysema
systemic scleroderma
Weill-Marchesani syndrome
14118 (NCBI Gene Model)
Q61554 (UniProt | EBI)
NM_007993 (RefSeq)
rat Fbn1 83727 (Entrez Gene)
Chr3 q36 NP_114013 (RefSeq)
NM_031825 (RefSeq)
chimpanzee FBN1 453411 (Entrez Gene)
Chr15 XP_001149266 (RefSeq)
cattle FBN1 281154 (Entrez Gene)
Chr10 P98133 (UniProt | EBI)
NM_174053 (RefSeq)
dog FBN1 478293 (Entrez Gene)
Chr30 NP_001274014 (RefSeq)
NM_001287085 (RefSeq)
chicken FBN1 373992 (Entrez Gene)
Chr10 XP_015147421 (RefSeq)
frog, western clawed fbn1 100490545 (Entrez Gene)
Chr3 XP_002936615 (RefSeq)
macaque, rhesus FBN1 714451 (Entrez Gene)
Chr7 XP_014997668 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory