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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
30958

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FBN1 HGNC:3603 (HGNC)
2200 (Entrez Gene)
134797 (OMIM)
Chr15 q21.1 Chr15:48408306-48645788 (-)
GRCh38
Acromicric Dysplasia; ACMICD
Ectopia Lentis 1, Isolated, Autosomal Dominant; ECTOL1
Geleophysic Dysplasia 2; GPHYSD2
Marfan Syndrome; MFS
MASS Syndrome
Stiff Skin Syndrome; SSKS
Weill-Marchesani Syndrome 2; WMS2
P35555 (UniProt | EBI)
NM_000138 (RefSeq)
mouse Fbn1 MGI:95489 (MGI)
14118 (Entrez Gene)
Gene Tree
VISTA-Point
Chr2 61.38 cM Chr2:125300594-125507993 (-)
GRCm38
Emphysema, Hereditary Pulmonary
Marfan Syndrome; MFS
Scleroderma, Familial Progressive
Weill-Marchesani Syndrome 2; WMS2
OTTMUSG00000015332 (VEGA)
OTTMUSP00000016325 (VEGA)
OTTMUST00000036335 (VEGA)
rat Fbn1 83727 (Entrez Gene)
Chr3 q36 NP_114013 (RefSeq)
NM_031825 (RefSeq)
chimpanzee FBN1 453411 (Entrez Gene)
Chr15 XP_001149266 (RefSeq)
rhesus macaque FBN1 714451 (Entrez Gene)
Chr7 XP_001113107 (RefSeq)
cattle FBN1 281154 (Entrez Gene)
Chr10 P98133 (UniProt | EBI)
NM_174053 (RefSeq)
dog FBN1 478293 (Entrez Gene)
Chr30 NP_001274014 (RefSeq)
NM_001287085 (RefSeq)
chicken FBN1 373992 (Entrez Gene)
Chr10 XP_413815 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory