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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human APOE HGNC:613 (HGNC)
348 (Entrez Gene)
107741 (OMIM)
Apolipoprotein E (MyGene.info)
HGNC homology
Chr19 q13.32 Chr19:44905749-44909395 (+)
age related macular degeneration 1
Alzheimer's disease 2
Alzheimer's disease 4
hyperlipoproteinemia type III
sea-blue histiocytosis
P02649 (UniProt | EBI)
NM_001302690 (RefSeq)
mouse Apoe MGI:88057 (MGI)
11816 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 9.94 cM Chr7:19696109-19699188 (-)
ENSMUSG00000002985 (Ensembl Gene Model)
ENSMUSP00000133371 (Ensembl)
ENSMUST00000173739 (Ensembl)
rat Apoe 25728 (Entrez Gene)
Chr1 q21 P02650 (UniProt | EBI)
NM_001270684 (RefSeq)
chimpanzee APOE 449586 (Entrez Gene)
Chr19 Q9GJU3 (UniProt | EBI)
NM_001009007 (RefSeq)
cattle APOE 281004 (Entrez Gene)
Chr18 q24 Q03247 (UniProt | EBI)
NM_173991 (RefSeq)
dog APOE 476438 (Entrez Gene)
Chr1 P18649 (UniProt | EBI)
frog, western clawed apoe 394678 (Entrez Gene)
Chr7 XP_002941085 (RefSeq)
macaque, rhesus APOE 714623 (Entrez Gene)
Chr19 Q28502 (UniProt | EBI)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory