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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EIF2S1 HGNC:3265 (HGNC)
1965 (Entrez Gene)
603907 (OMIM)
EIF2S1 (MyGene.info)
HGNC homology
Chr14 q23.3 Chr14:67360317-67386516 (+)
P05198 (UniProt | EBI)
NM_004094 (RefSeq)
mouse Eif2s1 MGI:95299 (MGI)
13665 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 35.51 cM Chr12:78862072-78887010 (+)
13665 (NCBI Gene Model)
Q6ZWX6 (UniProt | EBI)
NM_026114 (RefSeq)
rat Eif2s1 54318 (Entrez Gene)
Chr6 q24 P68101 (UniProt | EBI)
NM_019356 (RefSeq)
chimpanzee EIF2S1 452980 (Entrez Gene)
Chr14 XP_510016 (RefSeq)
cattle EIF2S1 327694 (Entrez Gene)
Chr10 P68102 (UniProt | EBI)
NM_175813 (RefSeq)
dog EIF2S1 480361 (Entrez Gene)
Chr8 XP_005623592 (RefSeq)
chicken EIF2S1 423279 (Entrez Gene)
Chr5 Q5ZLX2 (UniProt | EBI)
NM_001006477 (RefSeq)
zebrafish eif2s1a 321807 (Entrez Gene)
Chr17 NP_955863 (RefSeq)
NM_199569 (RefSeq)
eif2s1b 321564 (Entrez Gene)
Chr20 NP_571875 (RefSeq)
NM_131800 (RefSeq)
frog, western clawed eif2s1 448087 (Entrez Gene)
Chr8 Q6GL89 (UniProt | EBI)
NM_001005630 (RefSeq)
macaque, rhesus EIF2S1 710150 (Entrez Gene)
Chr7 NP_001244395 (RefSeq)
NM_001257466 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory