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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ABCA4 HGNC:34 (HGNC)
24 (Entrez Gene)
601691 (OMIM)
ABCA4 (MyGene.info)
HGNC homology
Chr1 p22.1 Chr1:93992837-94121149 (-)
age related macular degeneration 2
cone-rod dystrophy 3
retinitis pigmentosa 19
Stargardt disease
P78363 (UniProt | EBI)
NM_000350 (RefSeq)
mouse Abca4 MGI:109424 (MGI)
11304 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 52.94 cM Chr3:122044443-122180123 (+)
cone-rod dystrophy 3
retinitis pigmentosa 19
Stargardt disease
ENSMUSG00000028125 (Ensembl Gene Model)
ENSMUSP00000013995 (Ensembl)
ENSMUST00000013995 (Ensembl)
rat Abca4 310836 (Entrez Gene)
Chr2 q41 NP_001101191 (RefSeq)
NM_001107721 (RefSeq)
chimpanzee ABCA4 745972 (Entrez Gene)
Chr1 XP_009423955 (RefSeq)
cattle ABCA4 281584 (Entrez Gene)
Chr3 NP_776646 (RefSeq)
NM_174221 (RefSeq)
dog ABCA4 444852 (Entrez Gene)
Chr6 NP_001003360 (RefSeq)
NM_001003360 (RefSeq)
chicken ABCA4 424490 (Entrez Gene)
Chr8 XP_015146192 (RefSeq)
zebrafish abca4b 555506 (Entrez Gene)
Chr2 XP_005163385 (RefSeq)
frog, western clawed abca4 496442 (Entrez Gene)
Chr4 NP_001011033 (RefSeq)
NM_001011033 (RefSeq)
macaque, rhesus ABCA4 714054 (Entrez Gene)
Chr1 XP_015000846 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory