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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SOCS3 HGNC:19391 (HGNC)
9021 (Entrez Gene)
604176 (OMIM)
SOCS3 (MyGene.info)
HGNC homology
Chr17 q25.3 Chr17:78356777-78360079 (-)
O14543 (UniProt | EBI)
NM_003955 (RefSeq)
mouse Socs3 MGI:1201791 (MGI)
12702 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 82.96 cM Chr11:117966079-117970047 (-)
ENSMUSG00000053113 (Ensembl Gene Model)
ENSMUSP00000059129 (Ensembl)
ENSMUST00000054002 (Ensembl)
rat Socs3 89829 (Entrez Gene)
Chr10 q32.2 O88583 (UniProt | EBI)
NM_053565 (RefSeq)
chimpanzee SOCS3 454921 (Entrez Gene)
Chr17 XP_001157032 (RefSeq)
cattle SOCS3 282081 (Entrez Gene)
Chr19 Q9BEG9 (UniProt | EBI)
NM_174466 (RefSeq)
dog SOCS3 442949 (Entrez Gene)
Chr9 Q68AM8 (UniProt | EBI)
NM_001031631 (RefSeq)
chicken SOCS3 395299 (Entrez Gene)
Chr18 Q90X67 (UniProt | EBI)
NM_204600 (RefSeq)
zebrafish socs3a 335409 (Entrez Gene)
Chr3 NP_956244 (RefSeq)
NM_199950 (RefSeq)
socs3b 406596 (Entrez Gene)
Chr12 NP_998469 (RefSeq)
NM_213304 (RefSeq)
frog, western clawed socs3 448204 (Entrez Gene)
Chr10 NP_001005696 (RefSeq)
NM_001005696 (RefSeq)
macaque, rhesus SOCS3 715680 (Entrez Gene)
Chr16 NP_001181255 (RefSeq)
NM_001194326 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory