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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human EIF2B5 HGNC:3261 (HGNC)
8893 (Entrez Gene)
603945 (OMIM)
EIF2B5 (MyGene.info)
HGNC homology
Chr3 q27.1 Chr3:184134435-184145311 (+)
leukoencephalopathy with vanishing white matter
Q13144 (UniProt | EBI)
NM_003907 (RefSeq)
mouse Eif2b5 MGI:2446176 (MGI)
224045 (Entrez Gene)
Gene Tree
HGNC homology
Chr16 12.45 cM Chr16:20498817-20509323 (+)
leukoencephalopathy with vanishing white matter
ENSMUSG00000003235 (Ensembl Gene Model)
ENSMUSP00000003320 (Ensembl)
ENSMUST00000003320 (Ensembl)
rat Eif2b5 192234 (Entrez Gene)
Chr11 q23 Q64350 (UniProt | EBI)
NM_138866 (RefSeq)
chimpanzee EIF2B5 460881 (Entrez Gene)
Chr3 XP_001139517 (RefSeq)
cattle EIF2B5 783760 (Entrez Gene)
Chr1 XP_002684924 (RefSeq)
dog EIF2B5 100856343 (Entrez Gene)
Chr34 XP_022269848 (RefSeq)
chicken EIF2B5 424948 (Entrez Gene)
Chr9 XP_422755 (RefSeq)
zebrafish eif2b5 563613 (Entrez Gene)
Chr2 NP_001107069 (RefSeq)
NM_001113597 (RefSeq)
frog, western clawed eif2b5 100487780 (Entrez Gene)
Chr5 XP_002935185 (RefSeq)
macaque, rhesus EIF2B5 703673 (Entrez Gene)
Chr2 NP_001253050 (RefSeq)
NM_001266121 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory