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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SLC12A1 HGNC:10910 (HGNC)
6557 (Entrez Gene)
600839 (OMIM)
HGNC homology
Chr15 q21.1 Chr15:48206301-48304078 (+)
Bartter disease type 1
Q13621 (UniProt | EBI)
NM_001184832 (RefSeq)
mouse Slc12a1 MGI:103150 (MGI)
20495 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 61.23 cM Chr2:125152600-125230002 (+)
Bartter disease type 1
20495 (NCBI Gene Model)
P55014 (UniProt | EBI)
NM_001079690 (RefSeq)
rat Slc12a1 25065 (Entrez Gene)
Chr3 q36 P55016 (UniProt | EBI)
NM_001270618 (RefSeq)
chimpanzee SLC12A1 453410 (Entrez Gene)
Chr15 NP_001104309 (RefSeq)
NM_001110839 (RefSeq)
cattle SLC12A1 407161 (Entrez Gene)
Chr10 XP_002690982 (RefSeq)
dog SLC12A1 478292 (Entrez Gene)
Chr30 XP_013964903 (RefSeq)
chicken SLC12A1 415433 (Entrez Gene)
Chr10 XP_025009801 (RefSeq)
frog, western clawed slc12a1 100490198 (Entrez Gene)
Chr3 XP_012814934 (RefSeq)
macaque, rhesus SLC12A1 714289 (Entrez Gene)
Chr7 XP_014997660 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory