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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SCN4A HGNC:10591 (HGNC)
6329 (Entrez Gene)
603967 (OMIM)
Nav1.4 (MyGene.info)
HGNC homology
Chr17 q23.3 Chr17:63938554-63972918 (-)
congenital myasthenic syndrome 16
hyperkalemic periodic paralysis
hypokalemic periodic paralysis
P35499 (UniProt | EBI)
NM_000334 (RefSeq)
mouse Scn4a MGI:98250 (MGI)
110880 (Entrez Gene)
Gene Tree
HGNC homology
Chr11 68.91 cM Chr11:106318592-106353288 (-)
hyperkalemic periodic paralysis
hypokalemic periodic paralysis
OTTMUSG00000003417 (VEGA)
OTTMUSP00000003451 (VEGA)
OTTMUST00000007190 (VEGA)
rat Scn4a 25722 (Entrez Gene)
Chr10 q32.1 P15390 (UniProt | EBI)
NM_013178 (RefSeq)
chimpanzee SCN4A 100612017 (Entrez Gene)
Chr17 XP_016788230 (RefSeq)
cattle SCN4A 517426 (Entrez Gene)
Chr19 XP_005221045 (RefSeq)
dog SCN4A 610754 (Entrez Gene)
Chr9 XP_013971890 (RefSeq)
chicken SCN4A 771297 (Entrez Gene)
Chr27 NP_001305374 (RefSeq)
NM_001318445 (RefSeq)
zebrafish scn4aa 572442 (Entrez Gene)
Chr12 Q2XVR3 (UniProt | EBI)
NM_001039825 (RefSeq)
frog, western clawed scn4a 100492371 (Entrez Gene)
Chr10 XP_017944811 (RefSeq)
macaque, rhesus SCN4A 718194 (Entrez Gene)
Chr16 XP_014975582 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory