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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AGRN HGNC:329 (HGNC)
375790 (Entrez Gene)
103320 (OMIM)
Chr1 p36.33 Chr1:1020123-1056119 (+)
Myasthenic Syndrome, Congenital, with Pre- and Postsynaptic Defects;
O00468 (UniProt | EBI)
NM_198576 (RefSeq)
mouse Agrn MGI:87961 (MGI)
11603 (Entrez Gene)
Gene Tree
Chr4 88.55 cM Chr4:156165290-156197488 (-)
Myasthenia, Limb-Girdle, Familial
OTTMUSG00000011080 (VEGA)
OTTMUSP00000062908 (VEGA)
OTTMUST00000112089 (VEGA)
rat Agrn 25592 (Entrez Gene)
Chr5 q36 P25304 (UniProt | EBI)
NM_175754 (RefSeq)
chimpanzee AGRN 100609326 (Entrez Gene)
Chr7 XP_003319002 (RefSeq)
rhesus macaque AGRN 700400 (Entrez Gene)
Chr1 XP_001088755 (RefSeq)
cattle AGRN 525795 (Entrez Gene)
Chr16 XP_604151 (RefSeq)
dog AGRN 479574 (Entrez Gene)
Chr5 XP_536713 (RefSeq)
chicken AGRN 396538 (Entrez Gene)
Chr21 P31696 (UniProt | EBI)
NM_205527 (RefSeq)
western clawed frog agrn 100492176 (Entrez Gene)
ChrUN XP_002936430 (RefSeq)
zebrafish hm:gc12 565373 (Entrez Gene)
Chr23 NP_001170923 (RefSeq)
NM_001177452 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory