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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human AGRN HGNC:329 (HGNC)
375790 (Entrez Gene)
103320 (OMIM)
Agrin (MyGene.info)
HGNC homology
Chr1 p36.33 Chr1:1020102-1056119 (+)
congenital myasthenic syndrome 8
O00468 (UniProt | EBI)
NM_001305275 (RefSeq)
mouse Agrn MGI:87961 (MGI)
11603 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 88.55 cM Chr4:156165290-156197488 (-)
congenital myasthenic syndrome 8
OTTMUSG00000011080 (VEGA)
OTTMUSP00000062908 (VEGA)
OTTMUST00000112089 (VEGA)
rat Agrn 25592 (Entrez Gene)
Chr5 q36 P25304 (UniProt | EBI)
NM_175754 (RefSeq)
chimpanzee AGRN 100609326 (Entrez Gene)
Chr1 XP_009452985 (RefSeq)
cattle AGRN 525795 (Entrez Gene)
Chr16 XP_005217263 (RefSeq)
dog AGRN 479574 (Entrez Gene)
Chr5 XP_005620416 (RefSeq)
chicken AGRN 396538 (Entrez Gene)
Chr21 P31696 (UniProt | EBI)
NM_205527 (RefSeq)
zebrafish agrn 565373 (Entrez Gene)
Chr23 NP_001170923 (RefSeq)
NM_001177452 (RefSeq)
frog, western clawed agrn 100492176 (Entrez Gene)
Chr7 XP_017951502 (RefSeq)
macaque, rhesus AGRN 700400 (Entrez Gene)
Chr1 XP_014965958 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory