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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human IRS2 HGNC:6126 (HGNC)
8660 (Entrez Gene)
600797 (OMIM)
IRS2 (MyGene.info)
HGNC homology
Chr13 q34 Chr13:109753837-109786567 (-)
type 2 diabetes mellitus
Q9Y4H2 (UniProt | EBI)
NM_003749 (RefSeq)
mouse Irs2 MGI:109334 (MGI)
384783 (Entrez Gene)
Gene Tree
HGNC homology
Chr8 5.35 cM Chr8:10984681-11008458 (-)
type 2 diabetes mellitus
OTTMUSG00000059106 (VEGA)
OTTMUSP00000075523 (VEGA)
OTTMUST00000144972 (VEGA)
rat Irs2 29376 (Entrez Gene)
Chr16 q12.5 NP_001162104 (RefSeq)
NM_001168633 (RefSeq)
chimpanzee IRS2 452657 (Entrez Gene)
Chr13 XP_016781015 (RefSeq)
cattle IRS2 100300012 (Entrez Gene)
Chr12 XP_024855938 (RefSeq)
dog IRS2 485548 (Entrez Gene)
Chr22 XP_542667 (RefSeq)
chicken IRS2 428017 (Entrez Gene)
zebrafish irs2a 393285 (Entrez Gene)
Chr1 NP_956609 (RefSeq)
NM_200315 (RefSeq)
irs2b 572001 (Entrez Gene)
Chr9 XP_700746 (RefSeq)
frog, western clawed irs2 100498409 (Entrez Gene)
Chr2 XP_002933054 (RefSeq)
macaque, rhesus IRS2 698536 (Entrez Gene)
Chr17 XP_002800884 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory