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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human RB1 HGNC:9884 (HGNC)
5925 (Entrez Gene)
614041 (OMIM)
Retinoblastoma protein (MyGene.info)
HGNC homology
Chr13 q14.2 Chr13:48303747-48481890 (+)
lung small cell carcinoma
urinary bladder cancer
P06400 (UniProt | EBI)
NM_000321 (RefSeq)
mouse Rb1 MGI:97874 (MGI)
19645 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 38.73 cM Chr14:73183673-73325822 (-)
OTTMUSG00000036132 (VEGA)
OTTMUSP00000051423 (VEGA)
OTTMUST00000092874 (VEGA)
rat Rb1 24708 (Entrez Gene)
Chr15 q11 P33568 (UniProt | EBI)
NM_017045 (RefSeq)
chimpanzee RB1 452715 (Entrez Gene)
Chr13 XP_016781178 (RefSeq)
cattle RB1 534712 (Entrez Gene)
Chr12 q13 NP_001070375 (RefSeq)
NM_001076907 (RefSeq)
dog RB1 476915 (Entrez Gene)
Chr22 XP_022263996 (RefSeq)
chicken RB1 386582 (Entrez Gene)
Chr1 Q90600 (UniProt | EBI)
NM_204419 (RefSeq)
zebrafish rb1 777733 (Entrez Gene)
Chr21 NP_001071248 (RefSeq)
NM_001077780 (RefSeq)
frog, western clawed rb1 100493114 (Entrez Gene)
Chr2 NP_001269454 (RefSeq)
NM_001282525 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory