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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FAS HGNC:11920 (HGNC)
355 (Entrez Gene)
134637 (OMIM)
Fas receptor (MyGene.info)
HGNC homology
Chr10 q23.31 Chr10:88968429-89017061 (+)
autoimmune lymphoproliferative syndrome
P25445 (UniProt | EBI)
NM_152873 (RefSeq)
mouse Fas MGI:95484 (MGI)
14102 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 29.48 cM Chr19:34290659-34327770 (+)
autoimmune lymphoproliferative syndrome
Sjogren's syndrome
systemic lupus erythematosus
ENSMUSG00000024778 (Ensembl Gene Model)
ENSMUSP00000025691 (Ensembl)
ENSMUST00000025691 (Ensembl)
rat Fas 246097 (Entrez Gene)
Chr1 q52 Q63199 (UniProt | EBI)
NM_139194 (RefSeq)
chimpanzee FAS 738331 (Entrez Gene)
Chr10 XP_016774319 (RefSeq)
cattle FAS 282488 (Entrez Gene)
Chr26 q13 P51867 (UniProt | EBI)
NM_174662 (RefSeq)
dog FAS 486469 (Entrez Gene)
Chr26 XP_005636707 (RefSeq)
chicken FAS 395274 (Entrez Gene)
Chr6 NP_001186416 (RefSeq)
NM_001199487 (RefSeq)
zebrafish fas 768248 (Entrez Gene)
Chr17 XP_690447 (RefSeq)
frog, western clawed fas 100124750 (Entrez Gene)
Chr7 NP_001096199 (RefSeq)
NM_001102729 (RefSeq)
macaque, rhesus FAS 574332 (Entrez Gene)
Chr9 Q9BDP2 (UniProt | EBI)
NM_001032933 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory