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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
27

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FAS HGNC:11920 (HGNC)
355 (Entrez Gene)
134637 (OMIM)
Chr10 q24.1 Chr10:88969796-89017059 (+)
GRCh38
Autoimmune Lymphoproliferative Syndrome; ALPS
P25445 (UniProt | EBI)
NM_000043 (RefSeq)
mouse Fas MGI:95484 (MGI)
14102 (Entrez Gene)
Gene Tree
VISTA-Point
Chr19 29.48 cM Chr19:34290659-34327770 (+)
GRCm38
Autoimmune Lymphoproliferative Syndrome; ALPS
Diabetes Mellitus, Insulin-Dependent; IDDM
Sjogren Syndrome
Systemic Lupus Erythematosus; SLE
14102 (NCBI Gene Model)
P25446 (UniProt | EBI)
NM_007987 (RefSeq)
rat Fas 246097 (Entrez Gene)
Chr1 q52 Q63199 (UniProt | EBI)
NM_139194 (RefSeq)
chimpanzee FAS 738331 (Entrez Gene)
Chr10 XP_001139138 (RefSeq)
rhesus macaque FAS 574332 (Entrez Gene)
Chr9 Q9BDP2 (UniProt | EBI)
NM_001032933 (RefSeq)
dog FAS 486469 (Entrez Gene)
Chr26 XP_005636707 (RefSeq)
chicken FAS 395274 (Entrez Gene)
Chr6 NP_001186416 (RefSeq)
NM_001199487 (RefSeq)
zebrafish fas 768248 (Entrez Gene)
Chr17 XP_690447 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory