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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LTBP4 HGNC:6717 (HGNC)
8425 (Entrez Gene)
604710 (OMIM)
HGNC homology
Chr19 q13.1-q13.2 Chr19:40592888-40629820 (+)
Cutis Laxa, Autosomal Recessive, Type Ic; ARCL1C
Q8N2S1 (UniProt | EBI)
NM_001042544 (RefSeq)
mouse Ltbp4 MGI:1321395 (MGI)
108075 (Entrez Gene)
Gene Tree
HGNC homology
Chr7 15.87 cM Chr7:27305136-27337692 (-)
Cutis Laxa, Autosomal Recessive, Type Ic; ARCL1C
Pulmonary Disease, Chronic Obstructive; COPD
OTTMUSG00000031915 (VEGA)
OTTMUSP00000042166 (VEGA)
OTTMUST00000079136 (VEGA)
rat Ltbp4 292734 (Entrez Gene)
Chr1 q21 NP_001163807 (RefSeq)
NM_001170336 (RefSeq)
chimpanzee LTBP4 456044 (Entrez Gene)
Chr19 XP_009433904 (RefSeq)
cattle LTBP4 100848191 (Entrez Gene)
Chr18 XP_015313585 (RefSeq)
dog LTBP4 444849 (Entrez Gene)
Chr1 XP_533664 (RefSeq)
western clawed frog LOC100488208 100488208 (Entrez Gene)
ChrUN XP_002938859 (RefSeq)
zebrafish ltbp4 100333499 (Entrez Gene)
Chr18 XP_009292167 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory