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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PAX8 HGNC:8622 (HGNC)
7849 (Entrez Gene)
167415 (OMIM)
PAX8 (MyGene.info)
HGNC homology
Chr2 q14.1 Chr2:113215997-113278950 (-)
congenital nongoitrous hypothryoidism 2
Q06710 (UniProt | EBI)
NM_013951 (RefSeq)
mouse Pax8 MGI:97492 (MGI)
18510 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 16.43 cM Chr2:24420560-24475599 (-)
congenital hypothyroidism
OTTMUSG00000011957 (VEGA)
OTTMUSP00000012886 (VEGA)
OTTMUST00000028458 (VEGA)
rat Pax8 81819 (Entrez Gene)
Chr3 p13 P51974 (UniProt | EBI)
NM_031141 (RefSeq)
chimpanzee PAX8 459503 (Entrez Gene)
Chr2A XP_016804776 (RefSeq)
cattle PAX8 534661 (Entrez Gene)
Chr11 q22.1-q22.3 XP_614504 (RefSeq)
zebrafish pax8 60637 (Entrez Gene)
Chr5 XP_001339893 (RefSeq)
frog, western clawed pax8 780226 (Entrez Gene)
Chr3 A0JMA6 (UniProt | EBI)
NM_001079301 (RefSeq)
macaque, rhesus PAX8 701906 (Entrez Gene)
Chr13 XP_014968630 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory