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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TMC2 HGNC:16527 (HGNC)
117532 (Entrez Gene)
606707 (OMIM)
TMC2 (MyGene.info)
HGNC homology
Chr20 p13 Chr20:2536607-2642185 (+)
Q8TDI7 (UniProt | EBI)
NM_080751 (RefSeq)
mouse Tmc2 MGI:2151017 (MGI)
192140 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 63.19 cM Chr2:130195194-130264445 (+)
ENSMUSG00000060332 (Ensembl Gene Model)
ENSMUSP00000125843 (Ensembl)
ENSMUST00000166774 (Ensembl)
rat Tmc2 296153 (Entrez Gene)
Chr3 q36 NP_001099980 (RefSeq)
NM_001106510 (RefSeq)
chimpanzee TMC2 458045 (Entrez Gene)
Chr20 XP_009434980 (RefSeq)
cattle TMC2 515300 (Entrez Gene)
Chr13 NP_001107238 (RefSeq)
NM_001113766 (RefSeq)
dog TMC2 477179 (Entrez Gene)
Chr24 XP_005635398 (RefSeq)
chicken TMC2 428456 (Entrez Gene)
Chr2 NP_001034413 (RefSeq)
NM_001039324 (RefSeq)
zebrafish tmc2a 571240 (Entrez Gene)
Chr5 E7FFT2 (UniProt | EBI)
NM_001302237 (RefSeq)
frog, western clawed LOC100490320 100490320 (Entrez Gene)
macaque, rhesus TMC2 718161 (Entrez Gene)
Chr10 XP_015004873 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory