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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PKD1 HGNC:9008 (HGNC)
5310 (Entrez Gene)
601313 (OMIM)
PKD1 (MyGene.info)
HGNC homology
Chr16 p13.3 Chr16:2088708-2135898 (-)
polycystic kidney disease 1
P98161 (UniProt | EBI)
NM_000296 (RefSeq)
mouse Pkd1 MGI:97603 (MGI)
18763 (Entrez Gene)
Gene Tree
HGNC homology
Chr17 12.4 cM Chr17:24549950-24596514 (+)
autosomal recessive polycystic kidney disease
hypertrophic cardiomyopathy
polycystic kidney disease 1
18763 (NCBI Gene Model)
O08852 (UniProt | EBI)
NM_013630 (RefSeq)
rat Pkd1 24650 (Entrez Gene)
Chr10 q12 NP_001244281 (RefSeq)
NM_001257352 (RefSeq)
cattle PKD1 504986 (Entrez Gene)
Chr25 XP_024841200 (RefSeq)
dog PKD1 606755 (Entrez Gene)
Chr6 NP_001006651 (RefSeq)
NM_001006650 (RefSeq)
chicken PKD1 416553 (Entrez Gene)
Chr14 XP_015149930 (RefSeq)
zebrafish pkd1a 100149562 (Entrez Gene)
Chr1 XP_021333081 (RefSeq)
frog, western clawed pkd1 100494429 (Entrez Gene)
Chr9 XP_017952982 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory