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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SPRED2 HGNC:17722 (HGNC)
200734 (Entrez Gene)
609292 (OMIM)
Chr2 p14 Chr2:65307442-65432637 (-)
Q7Z698 (UniProt | EBI)
NM_181784 (RefSeq)
mouse Spred2 MGI:2150019 (MGI)
114716 (Entrez Gene)
Gene Tree
Chr11 12.79 cM Chr11:19924375-20024026 (+)
Achondroplasia; ACH
OTTMUSG00000005219 (VEGA)
OTTMUSP00000005403 (VEGA)
OTTMUST00000011644 (VEGA)
rat Spred2 305539 (Entrez Gene)
Chr14 q22 Q3C2P8 (UniProt | EBI)
NM_001047094 (RefSeq)
chimpanzee SPRED2 459284 (Entrez Gene)
Chr2A XP_009440845 (RefSeq)
rhesus macaque SPRED2 697196 (Entrez Gene)
Chr13 NP_001248029 (RefSeq)
NM_001261100 (RefSeq)
cattle SPRED2 519081 (Entrez Gene)
Chr11 XP_870472 (RefSeq)
dog SPRED2 481397 (Entrez Gene)
Chr10 XP_538517 (RefSeq)
chicken SPRED2 421271 (Entrez Gene)
Chr3 XP_419341 (RefSeq)
western clawed frog spred2 496441 (Entrez Gene)
ChrUN Q5Y171 (UniProt | EBI)
NM_001011032 (RefSeq)
zebrafish spred2b 793290 (Entrez Gene)
Chr13 Q6NYK3 (UniProt | EBI)
NM_213234 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory