About   Help   FAQ
HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
select all deselect all Go
human NKX2-1 HGNC:11825 (HGNC)
7080 (Entrez Gene)
600635 (OMIM)
NK2 homeobox 1 (MyGene.info)
HGNC homology
Chr14 q13.3 Chr14:36516397-36520225 (-)
choreatic disease
papillary thyroid carcinoma
P43699 (UniProt | EBI)
NM_003317 (RefSeq)
mouse Nkx2-1 MGI:108067 (MGI)
21869 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 24.42 cM Chr12:56531958-56536908 (-)
OTTMUSG00000044396 (VEGA)
OTTMUSP00000065278 (VEGA)
OTTMUST00000116868 (VEGA)
rat Nkx2-1 25628 (Entrez Gene)
Chr6 P23441 (UniProt | EBI)
NM_013093 (RefSeq)
chimpanzee NKX2-1 452867 (Entrez Gene)
Chr14 XP_009425981 (RefSeq)
cattle NKX2-1 613713 (Entrez Gene)
Chr21 NP_001178387 (RefSeq)
NM_001191458 (RefSeq)
chicken NKX2-1 395322 (Entrez Gene)
Chr5 NP_989947 (RefSeq)
NM_204616 (RefSeq)
zebrafish nkx2.1 81883 (Entrez Gene)
Chr17 NP_571851 (RefSeq)
NM_131776 (RefSeq)
frog, western clawed nkx2-1 100135015 (Entrez Gene)
Chr8 XP_002935383 (RefSeq)
macaque, rhesus NKX2-1 696771 (Entrez Gene)
Chr7 XP_014999072 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.11
The Jackson Laboratory