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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human LBR HGNC:6518 (HGNC)
3930 (Entrez Gene)
600024 (OMIM)
Lamin B receptor (MyGene.info)
HGNC homology
Chr1 q42.12 Chr1:225401502-225428855 (-)
Greenberg dysplasia
Pelger-Huet anomaly
Q14739 (UniProt | EBI)
NM_194442 (RefSeq)
mouse Lbr MGI:2138281 (MGI)
98386 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 84.89 cM Chr1:181815315-181842401 (-)
ichthyosis vulgaris
Pelger-Huet anomaly
systemic lupus erythematosus
98386 (NCBI Gene Model)
Q3U9G9 (UniProt | EBI)
NM_133815 (RefSeq)
rat Lbr 89789 (Entrez Gene)
Chr13 q26 O08984 (UniProt | EBI)
NM_134453 (RefSeq)
chimpanzee LBR 457776 (Entrez Gene)
Chr1 XP_514234 (RefSeq)
cattle LBR 509348 (Entrez Gene)
Chr16 NP_001093799 (RefSeq)
NM_001100329 (RefSeq)
dog LBR 490391 (Entrez Gene)
Chr7 XP_547512 (RefSeq)
chicken LBR 396285 (Entrez Gene)
Chr3 P23913 (UniProt | EBI)
NM_205342 (RefSeq)
zebrafish lbr 368360 (Entrez Gene)
Chr20 NP_001002720 (RefSeq)
NM_001002720 (RefSeq)
macaque, rhesus LBR 700801 (Entrez Gene)
Chr1 NP_001248262 (RefSeq)
NM_001261333 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory