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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TGFBR2 HGNC:11773 (HGNC)
7048 (Entrez Gene)
190182 (OMIM)
TGF beta receptor 2 (MyGene.info)
HGNC homology
Chr3 p24.1 Chr3:30606490-30694142 (+)
esophageal cancer
Loeys-Dietz syndrome
Lynch syndrome
P37173 (UniProt | EBI)
NM_001024847 (RefSeq)
mouse Tgfbr2 MGI:98729 (MGI)
21813 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 68.39 cM Chr9:116087695-116175363 (-)
cleft soft palate
DiGeorge syndrome
Loeys-Dietz syndrome
prostate cancer
21813 (NCBI Gene Model)
Q62312 (UniProt | EBI)
NM_009371 (RefSeq)
rat Tgfbr2 81810 (Entrez Gene)
Chr8 q32 P38438 (UniProt | EBI)
NM_031132 (RefSeq)
chimpanzee TGFBR2 460243 (Entrez Gene)
Chr3 XP_516343 (RefSeq)
cattle TGFBR2 535376 (Entrez Gene)
Chr22 NP_001153038 (RefSeq)
NM_001159566 (RefSeq)
dog TGFBR2 477039 (Entrez Gene)
Chr23 XP_005634388 (RefSeq)
chicken TGFBR2 396399 (Entrez Gene)
Chr2 Q90999 (UniProt | EBI)
NM_205428 (RefSeq)
zebrafish tgfbr2b 30739 (Entrez Gene)
Chr16 NP_878275 (RefSeq)
NM_182855 (RefSeq)
frog, western clawed tgfbr2 100488582 (Entrez Gene)
Chr6 XP_002941621 (RefSeq)
macaque, rhesus TGFBR2 703088 (Entrez Gene)
Chr2 NP_001248080 (RefSeq)
NM_001261151 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory