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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TBP HGNC:11588 (HGNC)
6908 (Entrez Gene)
600075 (OMIM)
HGNC homology
Chr6 q27 Chr6:170554333-170572870 (+)
Parkinson Disease, Late-Onset; PD
Spinocerebellar Ataxia 17; SCA17
P20226 (UniProt | EBI)
NM_001172085 (RefSeq)
mouse Tbp MGI:101838 (MGI)
21374 (Entrez Gene)
Gene Tree
Chr17 8.95 cM Chr17:15499888-15528379 (+)
Spinocerebellar Ataxia 17; SCA17
OTTMUSG00000030550 (VEGA)
OTTMUSP00000039699 (VEGA)
OTTMUST00000075644 (VEGA)
rat Tbp 117526 (Entrez Gene)
Chr1 q12 NP_001004198 (RefSeq)
NM_001004198 (RefSeq)
chimpanzee TBP 738472 (Entrez Gene)
Chr6 NP_001098077 (RefSeq)
NM_001104607 (RefSeq)
rhesus macaque TBP 696258 (Entrez Gene)
Chr4 XP_014993239 (RefSeq)
cattle TBP 516578 (Entrez Gene)
Chr9 Q2HJ52 (UniProt | EBI)
NM_001075742 (RefSeq)
dog TBP 611193 (Entrez Gene)
Chr12 XP_005627792 (RefSeq)
chicken TBP 395995 (Entrez Gene)
Chr3 O13270 (UniProt | EBI)
NM_205103 (RefSeq)
western clawed frog tbp 549093 (Entrez Gene)
ChrUN Q28GG8 (UniProt | EBI)
NM_001016339 (RefSeq)
zebrafish tbp 368882 (Entrez Gene)
Chr13 Q7SXL3 (UniProt | EBI)
NM_200096 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory