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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ADAM17 HGNC:195 (HGNC)
6868 (Entrez Gene)
603639 (OMIM)
ADAM17 (MyGene.info)
HGNC homology
Chr2 p25.1 Chr2:9488486-9555820 (-)
P78536 (UniProt | EBI)
NM_003183 (RefSeq)
mouse Adam17 MGI:1096335 (MGI)
11491 (Entrez Gene)
Gene Tree
HGNC homology
Chr12 8.3 cM Chr12:21323509-21373632 (-)
OTTMUSG00000021042 (VEGA)
OTTMUSP00000023112 (VEGA)
OTTMUST00000049767 (VEGA)
rat Adam17 57027 (Entrez Gene)
Chr6 q16 Q9Z1K9 (UniProt | EBI)
NM_020306 (RefSeq)
chimpanzee ADAM17 459018 (Entrez Gene)
Chr2A XP_515293 (RefSeq)
cattle ADAM17 517541 (Entrez Gene)
Chr11 XP_595713 (RefSeq)
dog ADAM17 475662 (Entrez Gene)
Chr17 NP_001273795 (RefSeq)
NM_001286866 (RefSeq)
chicken ADAM17 421931 (Entrez Gene)
Chr3 NP_001008682 (RefSeq)
NM_001008682 (RefSeq)
zebrafish adam17a 324142 (Entrez Gene)
Chr17 NP_955967 (RefSeq)
NM_199673 (RefSeq)
adam17b 560657 (Entrez Gene)
Chr20 XP_021324312 (RefSeq)
frog, western clawed adam17 100492947 (Entrez Gene)
Chr5 NP_001182159 (RefSeq)
NM_001195230 (RefSeq)
macaque, rhesus ADAM17 694429 (Entrez Gene)
Chr13 XP_014967169 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory