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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TMC1 HGNC:16513 (HGNC)
117531 (Entrez Gene)
606706 (OMIM)
HGNC homology
Chr9 q21.12 Chr9:72521801-72836351 (+)
Deafness, Autosomal Dominant 36; DFNA36
Deafness, Autosomal Recessive 7; DFNB7
Q8TDI8 (UniProt | EBI)
NM_138691 (RefSeq)
mouse Tmc1 MGI:2151016 (MGI)
13409 (Entrez Gene)
Gene Tree
Chr19 13.98 cM Chr19:20783458-20954202 (-)
Deafness, Autosomal Dominant 36; DFNA36
Deafness, Autosomal Recessive 7; DFNB7
ENSMUSG00000024749 (Ensembl Gene Model)
ENSMUSP00000040859 (Ensembl)
ENSMUST00000039500 (Ensembl)
rat Tmc1 361739 (Entrez Gene)
Chr1 q51 NP_001101991 (RefSeq)
NM_001108521 (RefSeq)
chimpanzee TMC1 472952 (Entrez Gene)
Chr9 XP_009455009 (RefSeq)
rhesus macaque TMC1 704827 (Entrez Gene)
Chr15 XP_014973432 (RefSeq)
cattle TMC1 538406 (Entrez Gene)
Chr8 XP_015327985 (RefSeq)
dog TMC1 484168 (Entrez Gene)
Chr1 XP_005616877 (RefSeq)
chicken TMC1 427255 (Entrez Gene)
ChrZ NP_001006580 (RefSeq)
NM_001006580 (RefSeq)
western clawed frog tmc1 100486683 (Entrez Gene)
ChrUN XP_002935639 (RefSeq)
zebrafish tmc1 567237 (Entrez Gene)
Chr5 NP_001299610 (RefSeq)
NM_001312681 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory