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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human TMC1 HGNC:16513 (HGNC)
117531 (Entrez Gene)
606706 (OMIM)
TMC1 (MyGene.info)
HGNC homology
Chr9 q21.13 Chr9:72521801-72836351 (+)
autosomal dominant nonsyndromic deafness 36
autosomal recessive nonsyndromic deafness 7
Q8TDI8 (UniProt | EBI)
NM_138691 (RefSeq)
mouse Tmc1 MGI:2151016 (MGI)
13409 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 13.98 cM Chr19:20783458-20954202 (-)
autosomal dominant nonsyndromic deafness 36
autosomal recessive nonsyndromic deafness 7
ENSMUSG00000024749 (Ensembl Gene Model)
ENSMUSP00000040859 (Ensembl)
ENSMUST00000039500 (Ensembl)
rat Tmc1 361739 (Entrez Gene)
Chr1 q51 NP_001101991 (RefSeq)
NM_001108521 (RefSeq)
chimpanzee TMC1 472952 (Entrez Gene)
Chr9 XP_016816447 (RefSeq)
cattle TMC1 538406 (Entrez Gene)
Chr8 XP_024851786 (RefSeq)
dog TMC1 484168 (Entrez Gene)
Chr1 XP_022283106 (RefSeq)
chicken TMC1 427255 (Entrez Gene)
ChrZ NP_001006580 (RefSeq)
NM_001006580 (RefSeq)
zebrafish tmc1 567237 (Entrez Gene)
Chr5 F1QFU0 (UniProt | EBI)
NM_001312681 (RefSeq)
frog, western clawed tmc1 100486683 (Entrez Gene)
Chr1 XP_002935639 (RefSeq)
macaque, rhesus TMC1 704827 (Entrez Gene)
Chr15 XP_014973432 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory