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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SORL1 HGNC:11185 (HGNC)
6653 (Entrez Gene)
602005 (OMIM)
HGNC homology
Chr11 q23.2-q24.2 Chr11:121452203-121633762 (+)
Alzheimer Disease; AD
Q92673 (UniProt | EBI)
NM_003105 (RefSeq)
mouse Sorl1 MGI:1202296 (MGI)
20660 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 23.55 cM Chr9:41964720-42124297 (-)
OTTMUSG00000031794 (VEGA)
OTTMUSP00000041931 (VEGA)
OTTMUST00000078792 (VEGA)
rat Sorl1 300652 (Entrez Gene)
Chr8 q22 NP_445971 (RefSeq)
NM_053519 (RefSeq)
chimpanzee LOC451626 451626 (Entrez Gene)
Chr11 XP_009422630 (RefSeq)
rhesus macaque SORL1 713011 (Entrez Gene)
Chr14 XP_014971461 (RefSeq)
cattle SORL1 533166 (Entrez Gene)
Chr15 NP_001179686 (RefSeq)
NM_001192757 (RefSeq)
dog SORL1 479408 (Entrez Gene)
Chr5 XP_536545 (RefSeq)
chicken SORL1 395998 (Entrez Gene)
Chr24 Q98930 (UniProt | EBI)
NM_001305160 (RefSeq)
western clawed frog sorl1 100490681 (Entrez Gene)
ChrUN XP_012822697 (RefSeq)
zebrafish sorl1 497306 (Entrez Gene)
Chr15 XP_005157607 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory