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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human ALS2 HGNC:443 (HGNC)
57679 (Entrez Gene)
606352 (OMIM)
Chr2 q33.1 Chr2:201700263-201781172 (-)
Amyotrophic Lateral Sclerosis 2, Juvenile; ALS2
Primary Lateral Sclerosis, Juvenile; PLSJ
Spastic Paralysis, Infantile-Onset Ascending; IAHSP
Q96Q42 (UniProt | EBI)
NM_020919 (RefSeq)
mouse Als2 MGI:1921268 (MGI)
74018 (Entrez Gene)
Gene Tree
Chr1 29.33 cM Chr1:59162926-59237231 (-)
OTTMUSG00000021752 (VEGA)
OTTMUSP00000024337 (VEGA)
OTTMUST00000051627 (VEGA)
rat Als2 363235 (Entrez Gene)
Chr9 q31 P0C5Y8 (UniProt | EBI)
NM_001013413 (RefSeq)
chimpanzee ALS2 470613 (Entrez Gene)
Chr2B Q5BIW4 (UniProt | EBI)
NM_001079920 (RefSeq)
rhesus macaque ALS2 703263 (Entrez Gene)
Chr12 XP_001091562 (RefSeq)
cattle ALS2 535750 (Entrez Gene)
Chr2 XP_615861 (RefSeq)
dog ALS2 100856109 (Entrez Gene)
Chr37 XP_003640234 (RefSeq)
chicken ALS2 424085 (Entrez Gene)
Chr7 XP_421940 (RefSeq)
western clawed frog als2 779575 (Entrez Gene)
ChrUN XP_004917812 (RefSeq)
zebrafish als2b 100318899 (Entrez Gene)
Chr6 XP_002662342 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory