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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
22876

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLCB1 HGNC:15917 (HGNC)
23236 (Entrez Gene)
607120 (OMIM)
Chr20 p12 Chr20:8132265-8884900 (+)
GRCh38
Epileptic Encephalopathy, Early Infantile, 12; EIEE12
Q9NQ66 (UniProt | EBI)
NM_015192 (RefSeq)
mouse Plcb1 MGI:97613 (MGI)
18795 (Entrez Gene)
Gene Tree
VISTA-Point
Chr2 65.66 cM Chr2:134786159-135475258 (+)
GRCm38
Alzheimer Disease; AD
Schizophrenia; SCZD
OTTMUSG00000015592 (VEGA)
OTTMUSP00000016610 (VEGA)
OTTMUST00000037031 (VEGA)
rat Plcb1 24654 (Entrez Gene)
Chr3 q36 P10687 (UniProt | EBI)
NM_001077641 (RefSeq)
chimpanzee PLCB1 469875 (Entrez Gene)
Chr20 XP_001170216 (RefSeq)
rhesus macaque PLCB1 718387 (Entrez Gene)
Chr10 NP_001244796 (RefSeq)
NM_001257867 (RefSeq)
cattle PLCB1 287026 (Entrez Gene)
Chr13 P10894 (UniProt | EBI)
NM_174817 (RefSeq)
dog PLCB1 485773 (Entrez Gene)
Chr24 XP_005634858 (RefSeq)
chicken PLCB1 427687 (Entrez Gene)
Chr3 XP_425261 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory