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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PLCB1 HGNC:15917 (HGNC)
23236 (Entrez Gene)
607120 (OMIM)
PLCB1 (MyGene.info)
HGNC homology
Chr20 p12.3 Chr20:8132236-8884911 (+)
early infantile epileptic encephalopathy 12
Q9NQ66 (UniProt | EBI)
NM_182734 (RefSeq)
mouse Plcb1 MGI:97613 (MGI)
18795 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 65.66 cM Chr2:134786164-135475258 (+)
Alzheimer's disease
18795 (NCBI Gene Model)
Q9Z1B3 (UniProt | EBI)
NM_019677 (RefSeq)
rat Plcb1 24654 (Entrez Gene)
Chr3 q36 P10687 (UniProt | EBI)
NM_001077641 (RefSeq)
chimpanzee PLCB1 469875 (Entrez Gene)
Chr20 XP_016792914 (RefSeq)
cattle PLCB1 287026 (Entrez Gene)
Chr13 P10894 (UniProt | EBI)
NM_174817 (RefSeq)
dog PLCB1 485773 (Entrez Gene)
Chr24 XP_013962331 (RefSeq)
chicken PLCB1 427687 (Entrez Gene)
Chr3 XP_025005027 (RefSeq)
macaque, rhesus PLCB1 718387 (Entrez Gene)
Chr10 NP_001244796 (RefSeq)
NM_001257867 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory