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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NPHS2 HGNC:13394 (HGNC)
7827 (Entrez Gene)
604766 (OMIM)
NPHS2 (MyGene.info)
HGNC homology
Chr1 q25.2 Chr1:179550539-179575987 (-)
nephrotic syndrome
Q9NP85 (UniProt | EBI)
NM_014625 (RefSeq)
mouse Nphs2 MGI:2157018 (MGI)
170484 (Entrez Gene)
Gene Tree
HGNC homology
Chr1 67.71 cM Chr1:156310727-156328035 (+)
nephrotic syndrome
OTTMUSG00000050345 (VEGA)
OTTMUSP00000068877 (VEGA)
OTTMUST00000127804 (VEGA)
rat Nphs2 170672 (Entrez Gene)
Chr13 q22 Q8K4G9 (UniProt | EBI)
NM_130828 (RefSeq)
chimpanzee NPHS2 100615219 (Entrez Gene)
Chr1 XP_016788875 (RefSeq)
cattle NPHS2 537633 (Entrez Gene)
Chr16 NP_001193036 (RefSeq)
NM_001206107 (RefSeq)
dog NPHS2 490323 (Entrez Gene)
Chr7 XP_022277414 (RefSeq)
chicken NPHS2 424422 (Entrez Gene)
Chr8 XP_422265 (RefSeq)
zebrafish nphs2 557914 (Entrez Gene)
Chr22 NP_001018155 (RefSeq)
NM_001018145 (RefSeq)
frog, western clawed nphs2 100498000 (Entrez Gene)
Chr4 XP_017949096 (RefSeq)
macaque, rhesus NPHS2 100430826 (Entrez Gene)
Chr1 XP_002802082 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory