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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 67, Dec 12, 2012)
228

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human NPC1 HGNC:7897 (HGNC)
4864 (Entrez Gene)
607623 (OMIM)
Chr18 q11.2 Chr18:23506184-23586617 (-)
GRCh38
Niemann-Pick Disease, Type C1; NPC1
O15118 (UniProt | EBI)
NM_000271 (RefSeq)
mouse Npc1 MGI:1097712 (MGI)
18145 (Entrez Gene)
Gene Tree
VISTA-Point
Chr18 6.15 cM Chr18:12189693-12236400 (-)
GRCm38
Niemann-Pick Disease, Type C1; NPC1
OTTMUSG00000028201 (VEGA)
OTTMUSP00000035538 (VEGA)
OTTMUST00000069856 (VEGA)
rat Npc1 266732 (Entrez Gene)
Chr18 p13 NP_705888 (RefSeq)
NM_153624 (RefSeq)
chimpanzee NPC1 455338 (Entrez Gene)
Chr18 XP_001155285 (RefSeq)
rhesus macaque NPC1 700835 (Entrez Gene)
Chr18 XP_002800934 (RefSeq)
cattle NPC1 286772 (Entrez Gene)
Chr24 NP_777183 (RefSeq)
NM_174758 (RefSeq)
dog NPC1 403698 (Entrez Gene)
Chr7 NP_001003107 (RefSeq)
NM_001003107 (RefSeq)
chicken NPC1 421076 (Entrez Gene)
Chr2 XP_419162 (RefSeq)
zebrafish npc1 553330 (Entrez Gene)
Chr2 NP_001230804 (RefSeq)
NM_001243875 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory