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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SCN5A HGNC:10593 (HGNC)
6331 (Entrez Gene)
600163 (OMIM)
HGNC homology
Chr3 p21 Chr3:38548058-38649673 (-)
Atrial Fibrillation, Familial, 10; ATFB10
Brugada Syndrome 1; BRGDA1
Cardiomyopathy, Dilated, 1E; CMD1E
Long QT Syndrome 3; LQT3
Progressive Familial Heart Block, Type IA; PFHB1A
Sick Sinus Syndrome 1, Autosomal Recessive; SSS1
Sudden Infant Death Syndrome
Ventricular Fibrillation, Paroxysmal Familial, 1; VF1
Q14524 (UniProt | EBI)
NM_001160160 (RefSeq)
mouse Scn5a MGI:98251 (MGI)
20271 (Entrez Gene)
Gene Tree
HGNC homology
Chr9 71.33 cM Chr9:119483410-119579016 (-)
Brugada Syndrome 1; BRGDA1
Cardiac Arrhythmia
Long QT Syndrome 3; LQT3
Progressive Familial Heart Block, Type IA; PFHB1A
OTTMUSG00000031832 (VEGA)
OTTMUSP00000042030 (VEGA)
OTTMUST00000078927 (VEGA)
rat Scn5a 25665 (Entrez Gene)
Chr8 q32 P15389 (UniProt | EBI)
NM_001160162 (RefSeq)
chimpanzee SCN5A 747523 (Entrez Gene)
Chr3 XP_001171891 (RefSeq)
rhesus macaque SCN5A 695085 (Entrez Gene)
Chr2 XP_002808375 (RefSeq)
cattle SCN5A 282061 (Entrez Gene)
Chr22 NP_776883 (RefSeq)
NM_174458 (RefSeq)
dog SCN5A 403497 (Entrez Gene)
Chr23 NP_001002994 (RefSeq)
NM_001002994 (RefSeq)
chicken SCN5A 395947 (Entrez Gene)
Chr2 XP_004939180 (RefSeq)
western clawed frog scn5a 100485924 (Entrez Gene)
ChrUN XP_012820422 (RefSeq)
zebrafish scn12aa 795688 (Entrez Gene)
Chr2 NP_001038387 (RefSeq)
NM_001044922 (RefSeq)
scn12ab 566868 (Entrez Gene)
Chr24 NP_001038588 (RefSeq)
NM_001045123 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory