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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
2255

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SDHB HGNC:10681 (HGNC)
6390 (Entrez Gene)
185470 (OMIM)
Chr1 p36.1-p35 Chr1:17018722-17054170 (-)
GRCh38
Cowden Syndrome 2; CWS2
Gastrointestinal Stromal Tumor; GIST
Paraganglioma and Gastric Stromal Sarcoma
Paragangliomas 4; PGL4
Pheochromocytoma Pheochromocytoma, Susceptibility to
P21912 (UniProt | EBI)
NM_003000 (RefSeq)
mouse Sdhb MGI:1914930 (MGI)
67680 (Entrez Gene)
Gene Tree
VISTA-Point
Chr4 73.24 cM Chr4:140961203-140979193 (+)
GRCm38
OTTMUSG00000010087 (VEGA)
OTTMUSP00000010715 (VEGA)
OTTMUST00000023450 (VEGA)
rat Sdhb 298596 (Entrez Gene)
Chr5 q36 P21913 (UniProt | EBI)
NM_001100539 (RefSeq)
chimpanzee SDHB 456526 (Entrez Gene)
Chr1 XP_001155516 (RefSeq)
rhesus macaque SDHB 699810 (Entrez Gene)
Chr1 NP_001248733 (RefSeq)
NM_001261804 (RefSeq)
cattle SDHB 286840 (Entrez Gene)
Chr2 Q3T189 (UniProt | EBI)
NM_001040483 (RefSeq)
dog SDHB 478217 (Entrez Gene)
Chr2 NP_001239146 (RefSeq)
NM_001252217 (RefSeq)
chicken SDHB 100859720 (Entrez Gene)
Chr21 Q9YHT2 (UniProt | EBI)
NM_001080875 (RefSeq)
western clawed frog sdhb 100144957 (Entrez Gene)
ChrUN B0BM36 (UniProt | EBI)
NM_001126528 (RefSeq)
zebrafish sdhb 562149 (Entrez Gene)
Chr22 A5PL98 (UniProt | EBI)
NM_001098740 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory