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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SDHB HGNC:10681 (HGNC)
6390 (Entrez Gene)
185470 (OMIM)
SDHB (MyGene.info)
HGNC homology
Chr1 p36.13 Chr1:17018722-17054170 (-)
Cowden disease
gastrointestinal stromal tumor
P21912 (UniProt | EBI)
NM_003000 (RefSeq)
mouse Sdhb MGI:1914930 (MGI)
67680 (Entrez Gene)
Gene Tree
HGNC homology
Chr4 73.24 cM Chr4:140961203-140979193 (+)
OTTMUSG00000010087 (VEGA)
OTTMUSP00000010715 (VEGA)
OTTMUST00000023450 (VEGA)
rat Sdhb 298596 (Entrez Gene)
Chr5 q36 P21913 (UniProt | EBI)
NM_001100539 (RefSeq)
chimpanzee SDHB 456526 (Entrez Gene)
Chr1 XP_001155516 (RefSeq)
cattle SDHB 286840 (Entrez Gene)
Chr2 Q3T189 (UniProt | EBI)
NM_001040483 (RefSeq)
dog SDHB 478217 (Entrez Gene)
Chr2 NP_001239146 (RefSeq)
NM_001252217 (RefSeq)
chicken SDHB 100859720 (Entrez Gene)
Chr21 Q9YHT2 (UniProt | EBI)
NM_001080875 (RefSeq)
zebrafish sdhb 562149 (Entrez Gene)
Chr22 A5PL98 (UniProt | EBI)
NM_001098740 (RefSeq)
frog, western clawed sdhb 100144957 (Entrez Gene)
ChrUN B0BM36 (UniProt | EBI)
NM_001126528 (RefSeq)
macaque, rhesus SDHB 699810 (Entrez Gene)
Chr1 NP_001248733 (RefSeq)
NM_001261804 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.10
The Jackson Laboratory