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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PTCH1 HGNC:9585 (HGNC)
5727 (Entrez Gene)
601309 (OMIM)
PTCH1 (MyGene.info)
HGNC homology
Chr9 q22.32 Chr9:95442982-95516965 (-)
basal cell carcinoma
holoprosencephaly 7
nevoid basal cell carcinoma syndrome
Q13635 (UniProt | EBI)
NM_001354918 (RefSeq)
mouse Ptch1 MGI:105373 (MGI)
19206 (Entrez Gene)
Gene Tree
HGNC homology
Chr13 32.8 cM Chr13:63508328-63573598 (-)
basal cell carcinoma
nevoid basal cell carcinoma syndrome
OTTMUSG00000050865 (VEGA)
OTTMUSP00000069299 (VEGA)
OTTMUST00000128873 (VEGA)
rat Ptch1 89830 (Entrez Gene)
Chr17 p14 NP_446018 (RefSeq)
NM_053566 (RefSeq)
chimpanzee PTCH1 465254 (Entrez Gene)
Chr9 XP_016816715 (RefSeq)
cattle PTCH1 520994 (Entrez Gene)
Chr8 NP_001192808 (RefSeq)
NM_001205879 (RefSeq)
dog PTCH1 484137 (Entrez Gene)
Chr1 XP_003638919 (RefSeq)
chicken PTCH1 395806 (Entrez Gene)
ChrZ Q90693 (UniProt | EBI)
NM_204960 (RefSeq)
zebrafish ptch1 30189 (Entrez Gene)
Chr8 NP_001292471 (RefSeq)
NM_001305542 (RefSeq)
frog, western clawed ptch1 100492061 (Entrez Gene)
Chr1 XP_002935019 (RefSeq)
macaque, rhesus PTCH1 718751 (Entrez Gene)
Chr15 XP_014973589 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory