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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human FHIT HGNC:3701 (HGNC)
2272 (Entrez Gene)
601153 (OMIM)
FHIT (MyGene.info)
HGNC homology
Chr3 p14.2 Chr3:59747278-61251474 (-)
P49789 (UniProt | EBI)
NM_001320900 (RefSeq)
mouse Fhit MGI:1277947 (MGI)
14198 (Entrez Gene)
Gene Tree
HGNC homology
Chr14 5.61 cM Chr14:9550092-11162035 (-)
Muir-Torre syndrome
OTTMUSG00000034621 (VEGA)
OTTMUSP00000047853 (VEGA)
OTTMUST00000087866 (VEGA)
rat Fhit 60398 (Entrez Gene)
Chr15 p15 Q9JIX3 (UniProt | EBI)
NM_021774 (RefSeq)
chimpanzee FHIT 747260 (Entrez Gene)
Chr3 XP_016795585 (RefSeq)
cattle FHIT 692183 (Entrez Gene)
Chr22 Q1KZG4 (UniProt | EBI)
NM_001040646 (RefSeq)
dog FHIT 100215999 (Entrez Gene)
Chr20 NP_001135729 (RefSeq)
NM_001142257 (RefSeq)
chicken FHIT 416071 (Entrez Gene)
Chr12 NP_001264733 (RefSeq)
NM_001277803 (RefSeq)
zebrafish fhit 393713 (Entrez Gene)
Chr6 NP_957034 (RefSeq)
NM_200740 (RefSeq)
LOC100331277 100331277 (Entrez Gene)
frog, western clawed fhit 448702 (Entrez Gene)
Chr4 NP_001006883 (RefSeq)
NM_001006882 (RefSeq)
macaque, rhesus FHIT 700974 (Entrez Gene)
Chr2 NP_001244750 (RefSeq)
NM_001257821 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory