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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SCN1A HGNC:10585 (HGNC)
6323 (Entrez Gene)
182389 (OMIM)
Nav1.1 (MyGene.info)
HGNC homology
Chr2 q24.3 Chr2:165989160-166149216 (-)
familial hemiplegic migraine
generalized epilepsy with febrile seizures plus
P35498 (UniProt | EBI)
NM_001353951 (RefSeq)
mouse Scn1a MGI:98246 (MGI)
20265 (Entrez Gene)
Gene Tree
HGNC homology
Chr2 39.13 cM Chr2:66270778-66440840 (-)
Dravet syndrome
generalized epilepsy with febrile seizures plus
OTTMUSG00000013102 (VEGA)
OTTMUSP00000014085 (VEGA)
OTTMUST00000031616 (VEGA)
rat Scn1a 81574 (Entrez Gene)
Chr3 q21 P04774 (UniProt | EBI)
NM_030875 (RefSeq)
chimpanzee SCN1A 459703 (Entrez Gene)
Chr2B XP_024210473 (RefSeq)
cattle SCN1A 529590 (Entrez Gene)
Chr2 NP_001180147 (RefSeq)
NM_001193218 (RefSeq)
dog SCN1A 478775 (Entrez Gene)
Chr36 XP_013966186 (RefSeq)
chicken SCN1A 771555 (Entrez Gene)
Chr7 XP_003641634 (RefSeq)
macaque, rhesus SCN1A 704086 (Entrez Gene)
Chr12 XP_001101115 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.11
The Jackson Laboratory