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Vertebrate Homology Class
Class ID
HomoloGene (Release 67, Dec 12, 2012)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SCN1A HGNC:10585 (HGNC)
6323 (Entrez Gene)
182389 (OMIM)
Chr2 q24.3 Chr2:165989160-166149132 (-)
Dravet Syndrome
Generalized Epilepsy with Febrile Seizures Plus, Type 2; GEFSP2
Migraine, Familial Hemiplegic, 3; FHM3
P35498 (UniProt | EBI)
NM_006920 (RefSeq)
mouse Scn1a MGI:98246 (MGI)
20265 (Entrez Gene)
Gene Tree
Chr2 39.13 cM Chr2:66270781-66440840 (-)
Dravet Syndrome
Generalized Epilepsy with Febrile Seizures Plus, Type 1; GEFSP1
OTTMUSG00000013102 (VEGA)
OTTMUSP00000014085 (VEGA)
OTTMUST00000031616 (VEGA)
rat Scn1a 81574 (Entrez Gene)
Chr3 q21 P04774 (UniProt | EBI)
NM_030875 (RefSeq)
chimpanzee SCN1A 459703 (Entrez Gene)
Chr2B XP_001154262 (RefSeq)
rhesus macaque SCN1A 704086 (Entrez Gene)
Chr12 XP_001100928 (RefSeq)
cattle SCN1A 529590 (Entrez Gene)
Chr2 NP_001180147 (RefSeq)
NM_001193218 (RefSeq)
dog SCN1A 478775 (Entrez Gene)
Chr36 XP_535941 (RefSeq)
chicken SCN1A 771555 (Entrez Gene)
Chr7 XP_001233839 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.17
The Jackson Laboratory