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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human PCSK5 HGNC:8747 (HGNC)
5125 (Entrez Gene)
600488 (OMIM)
PCSK5 (MyGene.info)
HGNC homology
Chr9 q21.13 Chr9:75890601-76362339 (+)
Q92824 (UniProt | EBI)
NM_001372043 (RefSeq)
mouse Pcsk5 MGI:97515 (MGI)
18552 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 12.86 cM Chr19:17432319-17837632 (-)
primary ciliary dyskinesia
VACTERL association
visceral heterotaxy
ENSMUSG00000024713 (Ensembl Gene Model)
ENSMUSP00000025618 (Ensembl)
ENSMUST00000025618 (Ensembl)
rat Pcsk5 116548 (Entrez Gene)
Chr1 q51 P41413 (UniProt | EBI)
NM_053823 (RefSeq)
chimpanzee PCSK5 464533 (Entrez Gene)
Chr9 XP_003312162 (RefSeq)
cattle PCSK5 528098 (Entrez Gene)
Chr8 XP_024851952 (RefSeq)
dog PCSK5 484160 (Entrez Gene)
Chr1 XP_022282911 (RefSeq)
chicken PCSK5 395456 (Entrez Gene)
ChrZ XP_015135840 (RefSeq)
zebrafish pcsk5a 571235 (Entrez Gene)
Chr5 XP_003198725 (RefSeq)
NM_001077582 (RefSeq)
frog, western clawed pcsk5 779961 (Entrez Gene)
Chr1 XP_012811365 (RefSeq)
NM_001079038 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory