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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SMAD2 HGNC:6768 (HGNC)
4087 (Entrez Gene)
601366 (OMIM)
HGNC homology
Chr18 q21.1 Chr18:47833095-47931193 (-)
Q15796 (UniProt | EBI)
NM_005901 (RefSeq)
mouse Smad2 MGI:108051 (MGI)
17126 (Entrez Gene)
Gene Tree
HGNC homology
Chr18 51.42 cM Chr18:76241580-76305731 (+)
OTTMUSG00000036536 (VEGA)
OTTMUSP00000052023 (VEGA)
OTTMUST00000093678 (VEGA)
rat Smad2 29357 (Entrez Gene)
Chr18 q12.3 O70436 (UniProt | EBI)
NM_001277450 (RefSeq)
chimpanzee SMAD2 455407 (Entrez Gene)
Chr18 XP_009432235 (RefSeq)
cattle SMAD2 516010 (Entrez Gene)
Chr24 Q1W668 (UniProt | EBI)
NM_001046218 (RefSeq)
dog SMAD2 480144 (Entrez Gene)
Chr7 XP_005622887 (RefSeq)
chicken SMAD2Z 395247 (Entrez Gene)
ChrZ NP_989892 (RefSeq)
NM_204561 (RefSeq)
zebrafish smad2 30639 (Entrez Gene)
Chr10 Q9I9P9 (UniProt | EBI)
NM_001290015 (RefSeq)
frog, western clawed smad2 496586 (Entrez Gene)
Chr1 NP_001011168 (RefSeq)
NM_001011168 (RefSeq)
macaque, rhesus SMAD2 697581 (Entrez Gene)
Chr18 NP_001253732 (RefSeq)
NM_001266803 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory