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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human JAK2 HGNC:6192 (HGNC)
3717 (Entrez Gene)
147796 (OMIM)
Janus kinase 2 (MyGene.info)
HGNC homology
Chr9 p24.1 Chr9:4985086-5128183 (+)
Budd-Chiari syndrome
essential thrombocythemia
familial erythrocytosis 1
polycythemia vera
O60674 (UniProt | EBI)
NM_001322199 (RefSeq)
mouse Jak2 MGI:96629 (MGI)
16452 (Entrez Gene)
Gene Tree
HGNC homology
Chr19 23.73 cM Chr19:29251828-29313080 (+)
essential thrombocythemia
polycythemia vera
ENSMUSG00000024789 (Ensembl Gene Model)
ENSMUSP00000064394 (Ensembl)
ENSMUST00000065796 (Ensembl)
rat Jak2 24514 (Entrez Gene)
Chr1 q52 Q62689 (UniProt | EBI)
NM_031514 (RefSeq)
chimpanzee JAK2 464979 (Entrez Gene)
Chr9 XP_016816046 (RefSeq)
cattle JAK2 525246 (Entrez Gene)
Chr8 XP_024851895 (RefSeq)
dog JAK2 484185 (Entrez Gene)
Chr1 XP_022277552 (RefSeq)
chicken JAK2 374199 (Entrez Gene)
ChrZ Q75R65 (UniProt | EBI)
NM_001030538 (RefSeq)
zebrafish jak2b 30298 (Entrez Gene)
Chr5 NP_571162 (RefSeq)
NM_131087 (RefSeq)
frog, western clawed jak2 100036599 (Entrez Gene)
Chr1 NP_001090634 (RefSeq)
NM_001097165 (RefSeq)
macaque, rhesus JAK2 694184 (Entrez Gene)
Chr15 NP_001252830 (RefSeq)
NM_001265901 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.12
The Jackson Laboratory